Among the residents of Tromaville is Melvin (Mitch Cohen), a nerdy janitor at the local health club. A gang of thugs devise a cruel hoax that goes horribly wrong and Melvin is cast through a third story window into a vat of toxic waste. However, an unexpected metamorphosis takes place. As the chemicals take hold of his body, Melvin turns into the Toxic Avenger, doer of good, and brutal mauler of evil! The excitement is non-stop as "Toxie" sets out to single handedly wipe out the forces of evil.

Arguably the most notorious 1980s horror comedy ever, The Toxic Avenger is still a classic over four decades later.